Overview of Picked Chemical Compounds and Intermediates
Overview of Picked Chemical Compounds and Intermediates
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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity associated with bortezomib, a proteasome inhibitor used in the treatment method of several myeloma. Its synthesis or research is crucial for making sure the purity and basic safety on the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-seven): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the therapy of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-one): A crucial compound in the synthesis of imatinib, a drug that targets precise sorts of cancer, which include Persistent myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers like breast, lung, and prostate most cancers.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, 8): They are intermediates during the synthesis of gemcitabine, an anti-cancer drug. Their analyze is essential for optimizing the output method and making sure superior purity.
Lapatinib Intermediate (CAS NO. 231278-84-5): Lapatinib is applied to treat breast cancer, and these intermediates are involved with its output.
Fulvestrant Intermediates: Fulvestrant is surely an estrogen receptor antagonist Employed in the treatment of breast cancer. Several intermediates assist in the synthesis of the drug.
Paclitaxel Facet Chain Acid (CAS NO. D-Gluconic acid 949023-16-nine): This intermediate is used in the synthesis of paclitaxel, a chemotherapy drug helpful in treating cancers like ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-3): A chemotherapy drug Utilized in the treatment method of colorectal most cancers and compact mobile lung most cancers.
three-Amino-one-hydroxyadamantane (CAS 702-eighty two-nine): This compound is involved with the synthesis of adamantane derivatives, that have a variety of purposes, which include antiviral lapatinib intermediate properties.
Vildagliptin Intermediates: Utilized in the creation of vildagliptin, an oral drug for style two diabetic issues that inhibits the enzyme DPP-four to manage blood sugar degrees.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is involved in the synthesis of various gluconic acid derivatives, that are used in foodstuff, pharmaceutical, and industrial apps.
Canagliflozin Intermediate 2: A precursor within the synthesis of canagliflozin, a medication applied to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).